PPIs for the Management of Upper GI Bleed
Introduction Upper GI bleed (UGIB) is a common reason for ED visits with a major cause of morbidity, mortality and medical care costs. Peptic ulcer…
Category: Pharmacy Friday Pearls
Single-Dose Aminoglycosides for UTIs
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Concomitant Parenteral Benzodiazepines and Olanzapine
Introduction Intramuscular olanzapine and parenteral benzodiazepines are commonly used agents in the ED for acute agitation. An FDA warning states that potentially fatal respiratory depression…
Alteplase for Acute Ischemic Stroke
Introduction Alteplase (rt-PA) has been used for acute ischemic stroke since its approval by the FDA in 1996 after publication of promising results of…
Hypertonic Saline Versus Mannitol for ICP Reduction
Introduction Elevated intracranial pressure (ICP) is caused by excess volume in the cerebral spaces, which causes a reduction in the cerebral perfusion pressure and…
Fosphenytoin vs Keppra for Status Epilepticus
Introduction Status epilepticus is a neurological emergency that required urgent assessment and treatment with pharmacologic agents Lorazepam and diazepam are short-acting drugs that can produce…
Management of Hypertensive Emergency
Introduction Hypertensive emergency is characterized by systolic blood pressure (SBP) > 180 mmHg or diastolic blood pressure (DBP) > 120 mmHg with evidence of target…
Fibrinolytics for STEMI
Introduction Percutaneous coronary intervention (PCI) is the preferred reperfusion strategy during a cardiac arrest; thrombolytic therapy is an option without PCI capability, followed by transfer…
Procainamide for Wide Complex Tachycardia
Introduction Ventricular tachycardia (VT) is an uncommon but dangerous medical condition, with an extremely variable clinical presentation. Intravenous procainamide is guideline recommended and is the…
Digoxin Poisoning Management
Digoxin Poisoning Management Pharmacy Friday Pearl – Pharmacy & Acute Care University Download PDF Handout Introduction Digoxin treats atrial flutter, atrial fibrillation, and heart failure. Toxicity occurs when…