Summary and References

In summary, this lesson has equipped pharmacists with a practical, evidence-based approach to integrating into ACLS and optimizing pharmacotherapy for cardiac arrest patients. We discussed cardiac arrest classification, ACLS protocols tailored to each rhythm, and pharmacological considerations to restore perfusion and organized electrical activity. Special topics like pediatrics, pregnancy, toxicology, and ethics were addressed. By understanding ACLS principles and the role of pharmacists therein, clinicians can help improve delivery of prompt, appropriate, and safe pharmacotherapy during cardiac arrest resuscitation.

References

1. 2015 American Heart Association Guidelines for CPR and ECC
2. ACLS Provider Manual (AHA)
3. Panchal AR et al. Part 3: Adult Basic and Advanced Life Support: 2020 American Heart Association Guidelines for CPR and ECC. Circulation. 2020;142(16_suppl_2):S366-S468.
4. Epinephrine [package insert]
5. Amiodarone [package insert]
6. Lidocaine [package insert]
7. Vasopressin [package insert]
8. Magnesium sulfate [package insert]
9. Naloxone [package insert]
10. Alteplase [package insert]