In this episode of PACUPod, we explore three fresh studies with immediate implications for acute care practice. First, we unpack a prospective trial comparing oxymetazoline, tranexamic acid, and an epinephrine–lidocaine mix for treating nosebleeds. Oxymetazoline emerges as the clear winner, demonstrating rapid, effective bleeding control—crucial for emergency settings.

Next, we delve into a phase II trial investigating whether IV salbutamol can alleviate renal colic pain. Despite its theoretical promise, the study found no significant benefit, adding nuance to the debate over non-traditional analgesics.

Finally, we tackle the perennial challenge of IV insertion pain. A head-to-head comparison of vapocoolant spray and lidocaine–prilocaine cream reveals comparable pain relief, but the spray’s immediacy and fewer side effects may give it the upper hand.

Tune in for these evidence-based updates, each ready to reshape your practice at the bedside.