- HCV-antibody testing
- HCV RNA polymerase chain reaction (PCR)
- Quantitative HCV-RNA prior to treatment initiation to document baseline level of viremia
- HCV genotype
- Cirrhosis assessment via liver fibrosis (Fibroscan or Fibrotest)
- Prior treatment history
- HCV-antibody testing likely to be positive once exposed; HCV RNA by PCR helps determine if current (active) infection
- Cirrhosis assessment via liver fibrosis (Fibroscan or Fibrotest)
- If F4, calculate Child-Pugh Score to determine cirrhotic state
- Compensated or decompensated
