
- Intensive Care Unit (ICU) or Stroke Unit admission
- Strict blood pressure monitoring
- Goal BP <180/105 mmHg
- Must be maintained during infusion and 24 hours after administration
- BP monitoring is as followed
- Every 15 minutes for 2 hours (from start of fibrinolytic therapy) then
- Every 30 minutes for 6 hours then
- Every hour for 16 hours
- Goal BP <180/105 mmHg
- Obtain follow up CT or MRI 24 hours after fibrinolytic treatment prior to initiating anticoagulation/antiplatelet agents