Seizure Prophylaxis in Traumatic Brain Injury by Jordan Spurling
Introduction Pharmacology Phenytoin Valproic Acid Levetiracetam Lacosamide Dose Loading dose: 17 to 20 mg/kg IV (max dose 2 g) Maintenance dose: 100 mg…
Category: Neurology
Alteplase for Acute Ischemic Stroke
Introduction Alteplase (rt-PA) has been used for acute ischemic stroke since its approval by the FDA in 1996 after publication of promising results of…
Hypertonic Saline Versus Mannitol for ICP Reduction
Introduction Elevated intracranial pressure (ICP) is caused by excess volume in the cerebral spaces, which causes a reduction in the cerebral perfusion pressure and…
Fosphenytoin vs Keppra for Status Epilepticus
Introduction Status epilepticus is a neurological emergency that required urgent assessment and treatment with pharmacologic agents Lorazepam and diazepam are short-acting drugs that can produce…