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Neurology 111

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  1. Hemorrhagic Stroke
    9 Topics
    |
    2 Quizzes
  2. Status Epilepticus
    10 Topics
    |
    2 Quizzes
  3. Myasthenia Gravis Exacerbation
    9 Topics
    |
    2 Quizzes
  4. Parkinson's Disease
    11 Topics
    |
    2 Quizzes
  5. Traumatic brain injury
    9 Topics
    |
    2 Quizzes
  6. Epilepsy
    9 Topics
    |
    2 Quizzes

Participants 396

  • Allison Clemens
  • April
  • ababaabhay
  • achoi2392
  • adhoward1
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Lesson 6, Topic 9
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Summary

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The treatment of epilepsy is a multifaceted and dynamic process that requires a deep understanding of its pathophysiology, clinical presentation, and diagnostic approaches. Effective management hinges on the careful selection and use of antiepileptic drugs (AEDs), which must be tailored to individual patient needs and seizure types. The course on “Pharmacotherapy for Epilepsy” provides healthcare professionals with comprehensive insights into the complexities of epilepsy treatment, including the latest advancements in AEDs, therapeutic drug monitoring, and the importance of considering drug interactions. Ultimately, the goal is to achieve optimal seizure control, minimize adverse effects, and enhance the overall quality of life for individuals with epilepsy, while navigating the challenges and nuances of this evolving medical field.

References

  • Scheffer IE, Berkovic S, Capovilla G, et al. ILAE classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology. Epilepsia. 2017;58(4):512-521. doi:10.1111/epi.13709.
  • Fisher RS, Cross JH, D’Souza C, et al. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia. 2017;58(4):531-542. doi:10.1111/epi.13670.
  • Nguyen, Viet-Huong V., Dergalust, Sunita, & Chang, Edward. (2023). Chapter 75: Epilepsy. McGraw Hill. Page 51​​.
  • J Jr, Pedley TA, eds. Epilepsy: A Comprehensive Textbook. Lippincott Williams & Wilkins; 2008.
  • Krumholz A, Wiebe S, Gronseth GS, Gloss DS, Sanchez AM, Kabir AA, Liferidge AT, Martello JP, Kanner AM, Shinnar S, Hopp JL, French JA. Evidence-based guideline: Management of an unprovoked first seizure in adults: Report of the Guideline Development Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology. 2015 Apr 21;84(16):1705-13.
  • Patsalos PN, Spencer EP, Berry DJ. Therapeutic drug monitoring of antiepileptic drugs in epilepsy: A 2018 update. Ther Drug Monit. 2018;40(5):526–548.
  • Noachtar S, Peters AS. Semiology of epileptic seizures: A critical review. Epilepsy Behav. 2009;15(1):2–9. [PubMed: 19236941]
  • Felbatol [package insert]. Somerset, NJ: Meda Pharmaceuticals; August 2012.
  • Neurontin [package insert]. New York, NY: ParkeDavis; February 2018.
  • Topamax [package insert]. Titusville, NJ: Jannsen Pharmaceuticals; June 2018.
  • Zonegran [package insert]. Teaneck, NJ: Eisai Inc.; 2006.
  • Trileptal [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Inc.; March 2018.
  • Keppra [package insert]. Smyrna, GA: UCB Inc.; October 2017.
  • Lamictal [package insert]. Research Triangle Park, NC: GlaxoSmithKline; July 2018.
  • Gabitril [package insert]. Frazer, PA: Cephalon; April 2009.