Lesson 5,
Topic 3
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Pathophysiology
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Croup is caused by viral infection, most commonly parainfluenza virus. The virus infects the larynx, trachea, and bronchi, leading to mucosal edema and inflammation. This narrows the airway passages, increasing airway resistance. The narrowed airways create turbulent airflow, resulting in the characteristic inspiratory stridor. The increased airway resistance also leads to increased work of breathing.