PACULit Literature Updates August 2025: Pediatrics
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Assessments and ACPE4 Topics
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Pediatrics AAV9-Mediated Gene Therapy for Infantile-Onset Pompes Disease1 Topic|1 Quiz
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Early relapse during B lymphocyte depletion of children with frequently relapse steroid dependent nephrotic syndrome after rituximab treatment1 Topic|1 Quiz
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Prophylactic hydrocortisone and the risk of sepsis in neonates born extremely preterm1 Topic|1 Quiz
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Late Permissive Hypercapnia for Mechanically Ventilated Preterm Infants A Randomized Trial1 Topic|1 Quiz
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Reevaluating bicarbonate therapy in pediatric DKA A propensity scorematched analysis of neurological and respiratory outcomes1 Topic|1 Quiz
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Prehospital pain medication disparities among pediatric trauma patients transported to a single Level I center1 Topic|1 Quiz
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Pediatric respiratory syncytial virus rehospitalization rate a retrospective observational study from Switzerland1 Topic|1 Quiz
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A Simplified Regional Lung Ultrasound Score for Surfactant Administration in Neonatal RDS A Prospective Observational Study1 Topic
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Dupilumab Plus Medium-Dose Inhaled Corticosteroid ICS Improves Outcomes Compared With Placebo Plus Continued HighDose ICS in Children With Uncontrolled ModeratetoSevere Type 2 Asthma1 Topic|1 Quiz
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Clinical Decision Support for Septic Shock in the Emergency Department A Cluster Randomized Trial1 Topic|1 Quiz
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Pediatric respiratory syncytial virus rehospitalization rate a retrospective observational study from Switzerland
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Question 1 of 3
1. Question
A 10-month-old male infant born prematurely at 34 weeks gestation was hospitalized for severe RSV bronchiolitis during the current RSV season. He has a history of mild bronchopulmonary dysplasia and is currently on supplemental oxygen at home. The infant’s parents inquire about the need for an additional dose of monoclonal antibody prophylaxis to prevent RSV rehospitalization within the same season.
Based on the findings from the Swiss retrospective study on RSV rehospitalization, what is the most appropriate pharmacist recommendation regarding the administration of a second dose of monoclonal antibody for same-season RSV prevention in this patient?
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Question 2 of 3
2. Question
A 3-year-old female child with a history of congenital heart disease and previous hospitalization for RSV bronchiolitis at 6 months of age presents for a routine medication review. Her parents are concerned about her risk of future RSV-related hospitalizations and ask about preventive strategies.
Which of the following statements best reflects the risk factors for RSV rehospitalization identified in the Swiss study and the implications for pharmacist counseling?
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Question 3 of 3
3. Question
A 2-year-old boy with a history of RSV hospitalization at 8 months is readmitted for RSV infection during a subsequent RSV season. The healthcare team asks the pharmacist about expected clinical outcomes and length of stay compared to the initial hospitalization.
According to the retrospective study from Switzerland, what is the expected difference in length of hospital stay (LoS) for RSV rehospitalizations compared to first hospitalizations, and how should this inform pharmacist communication with the clinical team?
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