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Lesson 12 of 16
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Rapid Sequence Intubation (RSI): Summary of Paralytics for RSI

The induction is for the patients but the paralytic is for the provider!

Summary of Paralytic Agents for RSI

DrugDoseOnsetDurationPearls
Succinylcholine1.5 mg/kg IV; 3-4 mg/
kg IM (maximum
150 mg
10-45 seconds
4-10 minutesMalignant
hyperthermia

Hyperkalemia

Patients at risk for
hyperkalemia
Rocuronium1-1.2 mg/kg IV
45-60 seconds 30-90 minutesInability to mask
ventilate

Vecuronium0.1-0.2 mg/kg IV
2-4 minutes 20-60 minutes Potential
prolonged
intubation

Summary of Paralytic Agents for RSI