Quick Review: Acute Ischemic Stroke (AIS)

Guidelines

• AHA/ASA Guidelines for the Early Management of Acute Ischemic Stroke

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Primary Literature

• Tissue plasminogen activator for acute ischemic stroke (NINDS)

• Hacke W, et al. “Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke” (ECASS III)

• Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II)

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Review Article

• Emergency Neurological Life Support: Acute Ischemic Stroke

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Podcast & Blogs

First10 EM: Thrombolytics for stroke: The evidence

EM Crit: Podcast 116 – the tPA for Ischemic Stroke Debate