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PACULit Literature Updates September 2025: Emergency Medicine & Critical Care

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  1. Use of a drug-related problem oriented medical record in the medication review of critically ill patients Randomized clinical trial
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    1 Quiz
  2. PACULit Daily Literature Update: Stress hyperglycemia ratio as a biomarker for early mortality risk stratification in cardiovascular disease a propensity matched analysis
    1 Topic
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    1 Quiz
  3. PACULit Daily Literature Update: Initial serum electrolyte imbalances and mortality in patients with traumatic brain injury a retrospective study
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    1 Quiz
    1. PACULit Daily Literature Update: Initial serum electrolyte imbalances and mortality in patients with traumatic brain injury a retrospective study
  4. PACULit Daily Literature Update: AsNeeded AlbuterolBudesonide in Mild Asthma
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    1 Quiz
  5. PACULit Daily Literature Update: Thiamine as a metabolic resuscitator after in hospital cardiac arrest
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    1 Quiz
  6. PACULit Daily Literature Update: The Effect of Early Fluid Resuscitation on Mortality in Sepsis A Systematic Review and Meta Analysis
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    1 Quiz
  7. PACULit Daily Literature Update: Inhaled isoflurane for sedation of mechanically ventilated children in intensive care (IsoCOMFORT): a multicentre, randomised, active-control, assessor-masked, non-inferiority phase 3 trial
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    1 Quiz
  8. PACULit Daily Literature Update: Prevalence risk factors and consequences of early clinical deterioration under noninvasive ventilation in emergency department patients a prospective multicentre observational study of the French IRU Network
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    1 Quiz
  9. PACULit Daily Literature Update: Evaluation of Stress Dose Hydrocortisone Tapers in Septic Shock
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    1 Quiz
  10. Opportunistic Screening for Atrial Fibrillation With Continuous ECG Monitoring in the Emergency Department
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    1 Quiz
  11. PACULit Daily Literature Update: Efficacy of targeting high mean arterial pressure for older patients with septic shock OPTPRESS a multicentre pragmatic open label randomised controlled trial
    1 Quiz
  12. PACULit Daily Literature Update: Evaluation of Etomidate Use and Association with Mortality Compared with Ketamine among Critically Ill Patients
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    1 Quiz
  13. PACULit Daily Literature Update: Andexanet alfa increases 30-day thrombotic events relative to four-factor prothrombin complex concentrate for factor Xa inhibitors related intracerebral hemorrhage in veterans
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    1 Quiz
  14. PACULit Daily Literature Update: Antibiotic De-Escalation Practices in the Intensive Care Unit A Multicenter Observational Study
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    1 Quiz
  15. PACULit Daily Literature Update: Fludrocortisone to treat patients with aneurysmal subarachnoid haemorrhage Protocol for an international phase 3 randomised placebocontrolled multicentre trial
    1 Topic
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    1 Quiz
  16. PACULit Daily Literature Update: Early intramuscular adrenaline administration is associated with improved survival from out-of-hospital cardiac arrest
    1 Topic
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    1 Quiz
  17. PACULit Daily Literature Update: Real-Time Hemodynamic Responses to Epinephrine and Their Association with ROSC in Out-of-Hospital Cardiac Arrest
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    1 Quiz
  18. Reevaluating bicarbonate therapy in pediatric DKA A propensity scorematched analysis of neurological and respiratory outcomes
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    1 Quiz
  19. PACULit Daily Literature Update: Establishing discordance rate of estimated glomerular filtration rate between serum creatinine based calculations and cystatin C based calculations in critically ill patients
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    1 Quiz
  20. Alteplase for Posterior Circulation Ischemic Stroke at 45 to 24 Hours
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    1 Quiz
  21. 2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines
    1 Topic
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    2 Quizzes
  22. ACPE Required Forms: PACULit Literature Updates September 2025: Emergency Medicine & Critical Care
    3 Topics

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  • Allison Clemens
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PACULit Literature Updates September 2025: Emergency Medicine & Critical Care PACULit Daily Literature Update: Initial serum electrolyte imbalances and mortality in patients with traumatic brain injury a retrospective study
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PACULit Daily Literature Update: Initial serum electrolyte imbalances and mortality in patients with traumatic brain injury a retrospective study

PACULit Daily Literature Update: Initial serum electrolyte imbalances and mortality in patients with traumatic brain injury a retrospective study

Mekkodathil A, El-Menyar A, Chughtai T, et al. Initial serum electrolyte imbalances and mortality in patients with traumatic brain injury: a retrospective study. World J Emerg Med. 2025 Jul;16(4):331-339. doi: 10.5847/wjem.j.1920-8642.2025.064. PMID: 40708737 | PMID: 40708737

Study Type

Retrospective Study

Population

Patients with Traumatic Brain Injury

Intervention

Initial Serum Electrolyte Measurement

Follow-up

Not reported

This retrospective study analyzed the association between initial serum electrolyte imbalances and mortality among patients with traumatic brain injury, highlighting the prognostic significance of early electrolyte disturbances.

Key Learning Points

  • •
    Initial serum electrolyte imbalances are significantly associated with increased mortality risk in patients with traumatic brain injury.
  • •
    Early assessment and correction of electrolyte disturbances are critical for improving outcomes in this patient population.


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