PACULit Daily Literature Update: Early intramuscular adrenaline administration is associated with improved survival from out-of-hospital cardiac arrest

Palatinus HN, Johnson MA, Wang HE, Hoareau GL, Youngquist ST. Early intramuscular adrenaline administration is associated with improved survival from out-of-hospital cardiac arrest. Resuscitation. 2024 Aug;201:110266. doi: 10.1016/j.resuscitation.2024.110266. Epub 2024 Jun 9. PMID: 38857847. | PMID: 38857847

This observational cohort study examined the association between early intramuscular adrenaline administration and survival outcomes in adults experiencing out-of-hospital cardiac arrest. The findings suggest improved survival rates are linked to early administration of intramuscular adrenaline compared to other routes.

Key Learning Points

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  Early administration of intramuscular adrenaline may improve survival rates in out-of-hospital cardiac arrest patients.
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  Intramuscular injection is a potentially effective and practical route for adrenaline in prehospital emergency settings.