Statins for STEMI in the Emergency Department
Introduction Pharmacology Atorvastatin Rosuvastatin Dose 80 mg orally once daily 40 mg orally once daily Administration Oral Oral PK/PD Onset: 3-5 days for LDL…
Tranexamic Acid in Trauma by Jordan Spurling
Introduction Pharmacology Tranexamic Acid Dose Loading dose: 1 g over 10 minutes started within 3 hours of injury2 gram via slow IV Push* …
How to Fail the BCEMP Exam
The Board Certified Emergency Medicine Pharmacotherapy (BCEMP) exam, offered by the Board of Pharmacy Specialties, represents a significant milestone for healthcare professionals specializing in emergency…
PROPHY-VAP Trial
The PROPHY-VAP trial showed that a single dose of ceftriaxone can significantly reduce early-onset VAP in mechanically ventilated brain-injured patien…
Piperacillin-tazobactam plus Vancomycin and Acute Kidney Injury by Caroline Rosario
Introduction Pharmacology Vancomycin Piperacillin-tazobactam4 Dose Depends on infection and PK/PD target General dosing for systemic infections: IV 15-20 mg/kg IV Q8-12H for systemic infections…
Seizure Prophylaxis in Traumatic Brain Injury by Jordan Spurling
Introduction Pharmacology Phenytoin Valproic Acid Levetiracetam Lacosamide Dose Loading dose: 17 to 20 mg/kg IV (max dose 2 g) Maintenance dose: 100 mg…
Penicillin Allergy Cross Reactivity
Introduction Pharmacology Group 1 Group 2 Group 3 Group 4 PenicillinCefoxitinCefuroxime AmoxicillinAmpicillinCefaclorCephalexinCefadroxil CeftriaxoneCefotaximeCefuroximeCefepimeCefpodoxime Ceftaroline AztreonamCeftolazane Ceftazidime Overview of Evidence Author Design Intervention & Comparison Outcome…
Corticosteroids in Sepsis by Marissa Marks, PharmD
Introduction Pharmacology Hydrocortisone Methylprednisolone Fludrocortisone Dose IV: 50 mg Q6H or 100 mg Q8H x 5-7 days IV (succinate): 40 to 125 mg/day (maximum…
Etomidate for RSI: Seizure Considerations
Introduction Rapid sequence intubation (RSI) is a process whereby an induction agent and a neuromuscular blocking agent are given in rapid succession to facilitate endotracheal…
Ketamine for Treatment of Acute Agitation
Introduction Ketamine is a sedative used for patients with extreme/refractory undifferentiated agitation Indications for utilizing ketamine for emergent sedation of agitated patients include Patient poses…