PACUlit Clinical Trials Dashboard
| Title | Disease States | Specialty | Summary Link |
|---|---|---|---|
| Annane D, et al. “Hydrocortisone plus Fludrocortisone for Adults with Septic Shock”. The New England Journal of Medicine. 2018. 378(9):809-818. | Sepsis |
Critical Care
|
Summary Link |
| Comparison of patient-controlled epidural analgesia with patient-controlled intravenous analgesia using pethidine or fentanyl. | Pain |
Pain & Sedation
|
Summary Link |
| Comparison of intramuscular and epidural morphine for postoperative analgesia in the grossly obese. | Pain |
Pain & Sedation
|
Summary Link |
| GUSTO Trial, 1993 | Acute Coronary Syndrome |
Cardiology
|
Summary Link |
| Undetectable high-sensitivity cardiac troponin T level in the emergency department and risk of myocardial infarction | Acute Coronary Syndrome |
Cardiology
|
Summary Link |
| GISSI-3 Group. “Effects of lisinopril and transdermal glyceryl trinitrate singly and together on 6-week mortality and ventricular function after acute myocardial infarction”. The Lancet. 1994. 343(8906):1115-22. | Acute Coronary Syndrome |
Cardiology
|
Summary Link |
| Efficacy and safety of topical ciprofloxacin/dexamethasone versus neomycin/polymyxin B/ hydrocortisone for otitis externa | Otitis Externa |
Pediatrics
|
Summary Link |
| Early goal-directed therapy in the treatment of severe sepsis and septic shock | N/A |
Critical Care Medicine
|
Summary Link |
| Clinical Efficacy of Beta-1 Selective Beta-Blockers Versus Propranolol in Patients With Thyroid Storm: A Retrospective Cohort Study | N/A |
Endocrinology
|
Summary Link |
| Evaluating a novel pharmacist-led buprenorphine outreach service for treatment of opioid use disorder in individuals residing in supportive housing | N/A |
Addiction Medicine
|
Summary Link |
| Aspirin and dipyridamole in the prevention of acute coronary thrombosis complicating coronary angioplasty | N/A |
Cardiology
|
Summary Link |
| A pharmacist-driven deprescribing protocol for negative urine and sexually transmitted infection cultures in the emergency department increases antibiotic-free days | N/A |
Emergency Medicine
Infectious Diseases
|
Summary Link |
| Impact of a calcium replacement protocol during massive transfusion in trauma patients at a level 2 trauma center | N/A |
Trauma Surgery/Internal Medicine
|
Summary Link |
| Nebulized medications in the emergency department: A narrative review of nontraditional agents | N/A |
Emergency Medicine
|
Summary Link |
| Rivaroxaban in Patients with a Recent Acute Coronary Syndrome | Acute Coronary Syndrome |
Cardiology
|
Summary Link |
| Rabies post-exposure prophylaxis in the emergency department | N/A |
Emergency Medicine
|
Summary Link |
| High-dose versus low-dose intravenous nitroglycerine for sympathetic crashing acute pulmonary edema: a randomised controlled trial | N/A |
Emergency Medicine
|
Summary Link |
| Ribociclib plus Endocrine Therapy in Early Breast Cancer | N/A |
Oncology
|
Summary Link |
| Effect of Thiamine Administration on Lactate Clearance and Mortality in Patients With Septic Shock | N/A |
Critical Care Medicine
|
Summary Link |
| Preparation/Administration of Push-Dose versus Continuous Infusion Epinephrine and Phenylephrine: A Simulation | N/A |
Emergency Medicine
|
Summary Link |
| Real world utilization of Andexanet alfa in the management of oral factor Xa inhibitor-associated gastrointestinal bleeding | Gastrointestinal Bleeding |
Hematology
|
Summary Link |
| Evaluating the impact of a discharge pharmacy in the emergency department on emergency department revisits and admissions | N/A |
Emergency Medicine
|
Summary Link |
| Tranexamic acid for angiotensin converting enzyme inhibitor induced angioedema: A retrospective multicenter study | N/A |
Emergency Medicine
|
Summary Link |
| Opioid Prescribing by Emergency Physicians: Trends Study of Medicare Part D Prescriber Data 2013-2019 | N/A |
Addiction Medicine
|
Summary Link |
| Prothrombin Complex Concentrate Administration Timing in Warfarin-Associated Intracranial Hemorrhage | N/A |
Hematology
|
Summary Link |
| Impact of emergency medicine clinical pharmacist practitioner-driven sepsis antibiotic interventions | N/A |
Pharmacy
|
Summary Link |
| Intermittent vs Continuous Proton Pump Inhibitor Therapy for High-Risk Bleeding Ulcers: A Systematic Review and Meta-analysis | N/A |
Gastroenterology
|
Summary Link |
| Operationalizing the new DEA exception: A novel process for dispensing of methadone for opioid use disorder at discharge from acute care settings | N/A |
Addiction Medicine
|
Summary Link |
| A comparison of low-molecular-weight heparin with unfractionated heparin for unstable coronary artery disease. Efficacy and Safety of Subcutaneous Enoxaparin in Non-Q-Wave Coronary Events Study Group | N/A |
Cardiology
|
Summary Link |
| Eplerenone, a Selective Aldosterone Blocker, in Patients with Left Ventricular Dysfunction after Myocardial Infarction | N/A |
Cardiology
|
Summary Link |
| Early intravenous then oral metoprolol in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial | Acute Coronary Syndrome |
Cardiology
|
Summary Link |
| Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction | N/A |
Cardiology
|
Summary Link |
| PEGASUS-TIMI 54. Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction | Acute Coronary Syndrome |
Cardiology
|
Summary Link |
| Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events | Secondary Prevention |
N/A
|
Summary Link |
| FRISC Investigators. “Invasive compared with non-invasive treatment in unstable coronary-artery disease: FRISC II prospective randomised multicentre study”. | Acute Coronary Syndrome |
Cardiology
|
Summary Link |
| CAPRICORN Trial Dargie HJ, et al. “Effect of carvedilol on outcome after myocardial infarction in patients with left-ventricular dysfunction: the CAPRICORN randomised trial”. The Lancet. 2001. 357(9266):1385-1390. | Acute Coronary Syndrome |
Cardiology
|
Summary Link |
| Cumulative epinephrine dose during cardiac arrest and neurologic outcome after extracorporeal cardiopulmonary resuscitation | Cardiac Arrest |
Resuscitation
|
Summary Link |
| Tenecteplase Compared with Alteplase for Acute Ischaemic Stroke in Canada (AcT) | N/A |
Emergency Medicine
Neurology
|
Summary Link |
| AURORA Study . Rosuvastatin and Cardiovascular Events in Patients Undergoing Hemodialysis” | Secondary Prevention |
N/A
|
Summary Link |
| Full-dose challenge of moderate, severe, and unknown beta-lactam allergies in the emergency department | Beta Lactam Allergy |
Emergency Medicine
|
Summary Link |
| Bhatt DL, et al. “Effect of Platelet Inhibition with Cangrelor during PCI on Ischemic Events”. The New England Journal of Medicine. 2013. 368(14):1303-1313. | Acute Coronary Syndrome |
Cardiology
|
Summary Link |
| CAST Trial. Mortality and morbidity in patients receiving Encainide, Flecainide, or Placebo | Ventricular Arrythima |
Cardiology
|
Summary Link |
| ECASS III | Acute Ischemic Stroke |
Neurology
|
Summary Link |
| A pharmacist-driven deprescribing protocol for negative urine and sexually transmitted infection cultures in the emergency department increases antibiotic-free days | Sexually Transmitted Disease, Urinary Tract Infection |
Emergency Medicine
|
Summary Link |
| ACURASYS | N/A |
Critical Care Medicine
|
Summary Link |
| TTM2: Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest | N/A |
Critical Care Medicine
|
Summary Link |
| BICAR-ICU | N/A |
Critical Care Medicine
|
Summary Link |